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The nation’s top infectious disease expert warned Sunday that more “pain and suffering” is on the horizon as COVID-19 cases climb again and officials plead with unvaccinated Americans to get their shots.

The latest guidance from the U.S. Centers for Disease Control and Prevention says people who are fully vaccinated should get tested three to five days after a potential exposure, even if they don’t have symptoms.

The Senate convened for a rare weekend session on Saturday, with Senate Majority Leader Chuck Schumer encouraging the authors of a bipartisan infrastructure plan to finish writing their bill so that senators can begin offering amendments.

A plan of action for climate change in Illinois. An exit interview with a 30-year veteran of the city. And a group of street vendors are now the proud owners of a shared kitchen.

While she was originally planning to stay for just the first year of Mayor Lori Lightfoot’s term, the pandemic delayed Rosa Escareño’s retirement plans – and gave her a firsthand seat to the massive blow COVID-19 dealt to the local economy.

Black and Latino neighborhoods in Chicago are more likely to be burdened by industries that pollute the air, ground and water, making environmental justice an important part of the equation as the country moves forward.

An Illinois tax agency has ruled that former President Donald Trump is due a $1 million refund on the 2011 tax bill for his downtown Chicago skyscraper, but local officials are trying to block the refund.

Conservative lawmakers made a push Thursday to boot Republican Reps. Liz Cheney and Adam Kinzinger out of the House GOP because the two defied party leaders and joined the chamber’s special committee investigating the Jan. 6 Capitol attack.

President Joe Biden has announced sweeping new pandemic requirements aimed at boosting vaccination rates for millions of federal workers and contractors as he lamented the “American tragedy” of rising-yet-preventable deaths among the unvaccinated.

New evidence showing the delta variant is as contagious as chickenpox and may be more dangerous than other versions has prompted U.S. health officials to consider changing advice on how the nation fights the coronavirus, internal documents show.

Fears spike that Lollapalooza will be a super-spreader event, with thousands of locals and tourists attending amid surging delta variant cases. Meanwhile, masking mandates make a comeback. Illinois Republicans battle each other over the Jan. 6 committee hearings. And the Cubs shed their World Series stars.

Everyone in Chicago, regardless of their vaccination status should wear a mask indoors, Chicago health officials recommended Friday after the Centers for Disease Control and Prevention added Chicago to its list of areas experiencing “substantial” transmission of the coronavirus.

More than a year after it was formed, the City Council’s Subcommittee on Reparations has met only once, and that meeting was sidetracked by a series of speakers who demanded that aldermen ban pet stores from selling dogs, cats and rabbits at a profit to restrict the operations of breeders.

In a 10-page ruling, Judge James Linn ordered that Jussie Smollett may continue using attorney Nenye Uche to represent him in the actor’s disorderly conduct case, despite a push from Special Prosecutor Dan Webb to have Uche removed.

Anthony Lorenzi was held without bail Friday following his arrest earlier this month in San Diego. He has since been extradited back to Cook County on a charge of first-degree murder in the killing of 24-year-old Gyovanny Arzuaga.

The Chicago Bungalow Association has announced the winners of its fifth annual garden contest, with winners spread across the city’s extensive bungalow belt.

The New York Yankees acquired Chicago Cubs first baseman Anthony Rizzo for two minor leaguers Thursday in their second major trade this week for desperately needed left-handed bats.

Can you still get COVID-19 after you’ve been fully vaccinated? Does the vaccine affect fertility? And does the vaccine alter DNA? Dr. John Segreti, hospital epidemiologist and medical director of infection control and prevention at Rush University Medical Center, weighs in.

The quintessential TV pitchman and inventor known to generations of viewers for hawking products including the Veg-O-Matic, the Pocket Fisherman, Mr. Microphone and the Showtime Rotisserie and BBQ, has died, his family said.

The Old World meets the new at a legendary Cicero restaurant that’s long served as an anchor for Chicago’s expansive Czech community. But now, its legacy is under threat.

The City Council has unanimously approved an ordinance to create an Urban Forestry Advisory Board — charged with strategically caring for Chicago's urban tree canopy.

As thousands of music lovers flocked to Grant Park for the first day of Lollapalooza, a surge of confirmed cases of COVID-19 in Chicago and the suburbs prompted Gov. J.B. Pritzker to reimpose a mask mandate in state facilities for everyone, regardless of their vaccination status.

A look inside Lollapalooza, where the show goes on despite a COVID-19 surge. How the global chip shortage impacts everything from cars to cellphones. A new city board charged with caring for trees.

The COVID-19 pandemic has caused the disruption of supply chains and manufacturing the world over. Manufacturers of computer chips in Asia have been especially hard hit. And that means companies that make products that rely on such chips are feeling the pinch.

It’s official: The Chicago Board of Education will transition from being an appointed body to an elected one — over the objections of Mayor Lori Lightfoot. 

The parent company of General Iron, which wants to operate a metal shredding and recycling operation on Chicago’s Southeast Side, failed to notify city officials that a vacant building collapsed on the site of the proposed facility, officials said Thursday.