If there’s one thing we’ve learned with certainty since the arrival of COVID-19 in the U.S., it’s that nothing is certain — least of all for the health care workers on the front lines of the crisis.

With critical protective equipment in short supply, Gov. J.B. Pritzker announced Wednesday the state has a new system to decontaminate N95 masks, allowing them to be used up to 20 times.

State Rep. John Cabello claims the governor “had no legal authority to act in ordering isolation or quarantine of citizens,” according to a lawsuit filed Wednesday — the second legal challenge to the governor’s stay-at-home order meant to curb the spread of COVID-19.

Star Farm in Back of the Yards makes up for in ambition what it lacks in size. Founder Stephanie Dunn’s mission is to use urban agriculture as the means of creating a healthier, more resilient community. 

A biotech company says its experimental drug has proved effective against the new coronavirus in a major U.S. government study that put it to a strict test.

From Cape Cod to California, festivals are being nixed, businesses in tourist havens are looking at empty reservation books, and people who have been cooped up through a dismal spring are worrying summer will bring just more of the same.

One of Chicago’s most well-known and outspoken priests, the Rev. Michael Pfleger of St. Sabina Church has spent years organizing anti-violence protests and measures around the city. 

The South Side community forms the bulk of a zip code that has seen 664 cases of COVID-19. Yet there are no public testing sites within the area, and few health centers equipped to administer them.

Home to many seniors and essential workers, Chicago’s Auburn Gresham neighborhood on the South Side has seen a disproportionately high rate of COVID-19 infections.

Public health officials on Tuesday reported 144 deaths over a 24-hour period, setting a new single-day record for fatalities linked to COVID-19. Across Illinois, 2,125 people have now died.

Starting Friday, Illinoisans must wear face masks in public. Ready to make your own? Cotton and other common fabrics, like natural silk and chiffon, are best, a new study finds.

More members of the Chicago Police Department have become ill than any other city department during the pandemic, with 414 officers testing positive for COVID-19 as of Monday, according to city data.

A conversation with Cicero Fire Chief Dominick Buscemi, who is part of the town’s emergency committee handling the pandemic response. 

Even in the shadow of the pandemic, gun violence in Chicago has not stopped. How the fight against COVID-19 is affecting the fight against violent crime.

Dr. Emily Landon’s job is to prepare for outbreaks like COVID-19. She joins us to discuss the effectiveness of testing and the statewide stay-at-home order.

A downstate judge issued a temporary restraining order Monday against the extension of Illinois’ stay-at-home order, a move the governor says risks the public’s health and safety.