Due to the surge of COVID-19 cases, the director of the U.S. Centers for Disease Control and Prevention is asking unvaccinated Americans not to travel during the Labor Day holiday weekend.

As the highly infectious delta variant continues to spread rapidly throughout the country, more children are testing positive for COVID-19. Could the return of in-person learning trigger even more cases?

Some of the biggest school systems in the U.S. are taking a hard line with teachers and staff members who are not yet vaccinated against COVID-19: Get a jab or lose your job. 

A statewide indoor mask mandate. A city worker vaccine mandate and police union pushback. Two Republican congressmen in jeopardy as remapping begins. And the country reels from an Afghanistan terror attack.

As the delta variant continues to drive a spike in COVID-19 cases, two recent reports outline the challenges of tracking so-called breakthrough cases in fully vaccinated people. We discuss the importance — and limitations — of disease surveillance.

After a weekslong surge in COVID-19 infections and hospitalizations, Gov. J.B. Pritzker on Thursday announced an indoor mask mandate for all Illinois residents and a vaccine requirement for pre-K through 12th grade teachers and staff, among others.

The mandate is likely to trigger a legal battle with the Fraternal Order of Police, Lodge 7, which represents the city’s 12,000 rank-and-file officers.

Military troops must immediately begin to get the COVID-19 vaccine, Defense Secretary Lloyd Austin said in a memo Wednesday, ordering service leaders to “impose ambitious timelines for implementation.” 

To open or not to open: That's been the question for Chicago’s performing arts community over the last year and a half. Now, the League of Chicago Theatres has announced new COVID-19 restrictions and safety measures as productions are set to fill up stages once again.

President Joe Biden says people who have been waiting for the FDA to formally approve a COVID-19 vaccine should get their shot now to stem what he calls a “pandemic of the unvaccinated.” Dr. Michael Angarone of Northwestern Medicine weighs in on that and more.

City workers will “absolutely” have to be vaccinated against COVID-19, Mayor Lori Lightfoot said Monday, promising a formal announcement in “days.”

The U.S. gave full approval to Pfizer’s COVID-19 vaccine Monday, a milestone that could boost public confidence in the shots and spur more companies, universities and local governments to make vaccinations mandatory.

Vaccine mandates are being put into place in some cities and sectors. Will those policies disproportionately disenfranchise the Black community, which lags behind in vaccination rates?

The order covers all of the employees who work for the office of Cook County Board President Toni Preckwinkle as well as those covered by Cook County Employment Plan, officials said.

Chicago has once again implemented an indoor mask requirement as the Biden administration announces a COVID-19 booster shot will be available for Americans starting in September. We talk to infectious disease expert Dr. Robert Murphy about the latest guidelines.

President Joe Biden on Wednesday announced that his administration will require that nursing home staff be vaccinated against COVID-19 as a condition for those facilities to continue receiving federal Medicare and Medicaid funding.