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A file photo of the University of Illinois at Urbana-Champaign. (WTTW News)

The University of Illinois posts its largest-ever endowment return. Crain’s Chicago Business editor Ann Dwyer has details on that story and more.

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(WTTW News)

Chicago’s second-largest bank by deposits is closing multiple branches by the end of the year. Crain’s Chicago Business editor Ann Dwyer takes us behind the headline of that story and more.

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Travelers wear masks at the airport in this file photo. (WTTW News)

It’s the last summer weekend to squeeze in a family vacation, but the delta variant of COVID-19 is discouraging Labor Day weekend travel. Crain’s Chicago Business editor Ann Dwyer takes us behind the headline of that story and more.

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(WTTW News)

Chicago home sales continue to rise, but there’s a twist in that fire-hot streak. Crain’s Chicago Business editor Ann Dwyer takes us behind the headline of that story and more.

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(Cytonn Photography / Unsplash)

Amazon Prime members who shop at Whole Foods in select cities, including Chicago, will soon see a new charge on their bills. Crain’s Chicago Business editor Ann Dwyer takes us behind the headline of that story and more.

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The Aon Center in Chicago. (WTTW News)

A merger that would have created the world’s largest insurance brokerage falls through. Crain’s Chicago Business editor Ann Dwyer takes us behind the headline of that story and more business news.

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A cutback in flights for a major airline. Crain’s Chicago Business editor Ann Dwyer takes us behind the headline of that story and more business news.

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(Raimond Spekking / Wikimedia Commons)

Good news for employees as air travel rebounds. Crain’s Chicago Business editor Ann Dwyer takes us behind the headline of that story and more.

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(WTTW News)

A massive buyout of a Chicago-area medical supply company. Crain’s Chicago Business editor Ann Dwyer takes us behind the headline of that story and more.

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(WTTW News)

The Chicago-based airline is encouraging frequent fliers to get vaccinated. Crain’s Chicago Business editor Ann Dwyer takes us behind the headline of that story and more.

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(WTTW News)

The number of daily flights from the Chicago-based airline is set to take off. Crain’s Chicago Business editor Ann Dwyer takes us behind the headline of that story and more.

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A CVS Pharmacy sign. (WTTW News)

Thousands of COVID-19 vaccines wasted at Walgreens and CVS. Crain’s Chicago Business editor Ann Dwyer takes us behind the headline of that story and more.

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(WTTW News via CNN)

Crop prices are expected to surge and spill over onto grocery shelves. Crain’s Chicago Business editor Ann Dwyer takes us behind the headline of that story and more.

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The Chicago Tribune Freedom Center printing facility along the Chicago River. (WTTW News)

The Chicago Tribune newspaper could become a nonprofit. Crain’s Chicago Business editor Ann Dwyer takes us behind the headline of that story and more.

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(WTTW News)

Chicago-based United Airlines takes a stand against the Georgia voting law. Crain’s Chicago Business editor Ann Dwyer takes us behind the headline of that story and more.

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The Loretto Hospital on Chicago’s West Side. (WTTW News)

Influential State Rep. Camille Lilly, a Loretto Hospital executive, is roped into the fallout over COVID-19 vaccines administered by the West Side safety net hospital. Crain’s Chicago Business editor Ann Dwyer takes us behind the headline of that story and more.