Stories by Associated Press

Iranian authorities say more than 200 people have been killed since the start of the strikes that killed Ayatollah Ali Khamenei and other senior leaders. The U.S. military said three service members have been killed, the first known American casualties from the conflict.

Iran retaliated by firing missiles and drones toward Israel and U.S. military bases in the region, and exchanges of fire continued into the night.

While presidents have the authority as the commander in chief to conduct certain strategic military operations on their own, the Constitution vests Congress with the power to wage war.

Since the 1990s, the FDA has collected fees from drug companies to help pay for extra staffers to quickly review new prescription drugs and vaccines. Under the agreement with the industry, the FDA has timelines and metrics for completing each review.

The remarks by two Iranian officials come as America has assembled its biggest deployment of aircraft and warships to the Middle East in decades. The buildup is part of President Donald Trump’s efforts to get a deal to constrain Iran’s nuclear program while the country struggles at home following nationwide protests.

President Donald Trump has delivered the State of the Union. Now the challenge for him is to make that message stick.

“It’s only gotten more complicated for everybody,’’ said trade lawyer Ryan Majerus, partner at King & Spalding and a former U.S. trade official.

The killing of Nemesio Oseguera Cervantes during an attempt to capture him in Jalisco state was the highest-profile blow against cartels since the recapture of former Sinaloa cartel boss Joaquín “El Chapo” Guzmán a decade ago.

House Speaker Mike Johnson’s office said it received a request from the family to have Jackson’s remains lie in honor at the Capitol, but the request was denied, because of the precedent that the space is typically reserved for former presidents, the military and select officials.

 The Supreme Court struck down President Donald Trump’s far-reaching global tariffs on Friday, handing him a significant loss on an issue crucial to his economic agenda.

The two-study standard for drugs dates to the early 1960s, when Congress passed a law requiring the FDA to review data from “adequate and well-controlled investigations” before clearing new medications.

The Rev. Jesse L. Jackson led a lifetime of crusades in the United States and abroad, advocating for the poor and underrepresented on issues from voting rights and job opportunities to education and health care.

Robert Duvall, the Oscar-winning actor whose classic roles included the intrepid consigliere of the first two “Godfather” movies and the over-the-hill country music singer in “Tender Mercies,” has died at age 95.

There’s now a growing push to separate profound autism — in which people need constant care for life, have a certain level of intellectual disability and are nonspeaking or minimally verbal — into its own diagnosis. The hope is that it would help ensure people get the support and services they need and that research includes them.

Environmental groups described the move as the single biggest attack in U.S. history against federal authority to address climate change. Evidence backing up the endangerment finding has only grown stronger in the 17 years since it was approved, they said.

Lawmakers continue to negotiate U.S. Department of Homeland Security funding, which Democrats are holding up over proposed reforms to immigration enforcement efforts.

Republicans said the legislation is needed to prevent voter fraud, but Democrats warn it will disenfranchise millions of Americans by making it harder to vote.

James Van Der Beek, a heartthrob who starred in coming-of-age dramas at the dawn of the new millennium, shooting to fame playing the titular character in “Dawson’s Creek” and in later years mocking his own hunky persona, has died. He was 48.

The shift comes as President Donald Trump’s administration pressures health care providers to limit or stop gender-affirming care for transgender people, particularly children.

The Trump administration is reducing the number of immigration officers in Minnesota but will continue its enforcement operation that has sparked weeks of tensions and deadly confrontations.

The last bill still to be worked out covers the Department of Homeland Security where Democrats are demanding more restrictions on enforcement operations.

Democrats are refusing to provide the votes House Speaker Mike Johnson needs to push the package forward as they try to rein in the Trump administration’s deportation operations after the shooting deaths of two Americans in Minneapolis.

The Canadian-born O’Hara died at her home in Los Angeles “following a brief illness,” according to a statement from her agency, Creative Artists Agency. Further details were not immediately available.

Journalist Don Lemon and three other people were arrested Friday in connection with an anti-immigration enforcement protest that disrupted a service at a Minnesota church and increased tensions between residents and federal officials.

The tariffs case took on added urgency because the consequences of the Trump administration’s policy were playing out in real time.

As the country reels from the deaths of two protesters at the hands of federal agents in Minneapolis, irate Senate Democrats laid out a list of demands on Wednesday, including that officers take off their masks and identify themselves and obtain warrants for arrest.