Indiana's passage of a so-called religious freedom law has sparked an angry backlash from those who assert that it gives license to businesses to discriminate against same-sex couples on religious grounds. Already there has been a massive backlash against the law, with leaders of business—including Apple's CEO Tim Cook—decrying the law.

First-term Ald. John Arena, a member of the City Council's Progressive Caucus and a frequent thorn in Mayor Rahm Emanuel's side, faces a runoff rematch with Chicago Police Lt. John Garrido in the race to represent the northwest side's 45th Ward.

Tracking the history and treatment of cancer from ancient Egypt through today: we talk with Dr. Siddhartha Mukherjee, author of the book The Emperor of All Maladies: A Biography of Cancer, about a new three-part documentary produced by Ken Burns that begins airing Monday, March 30 on WTTW11.

Chicago's own Ethel Payne was the third African-American to ever receive White House press credentials–and she was only the second black woman to do so. We talk with the author of a biography about the importance of her legacy.

The School Project is a Chicago-based documentary series that is tracking the past and present status of the city's public school system. The fourth episode  focuses on the battle over standardized testing.

We share what you had to say about Jesse Jackson Jr.'s release from prison, contract negotiations between CPS and CTU, and Chicago's urban coyotes in tonight's viewer feedback.

Contract negotiations between the Chicago Teachers Union and Chicago Public Schools have formally begun – and the union’s initial list of demands is not the traditional one. We have the details.

A French prosecutor announced Thursday that a Germanwings co-pilot deliberately crashed a jet in the French Alps after locking the pilot out of the cockpit. The prosecutor said there is no indication the crash was related to terrorism. The announcement has sparked questions about mental health evaluations for airline pilots, and why the co-pilot was able to prevent the pilot from gaining access to the cockpit. We have analysis.

First-term Ald. Michele Smith is fighting to keep her Lincoln Park aldermanic seat in a bitter battle with challenger Caroline Vickrey. They go head to head.

Ohio State University biologist Stanley Gehrt has followed more than 800 coyotes in Chicago over the past 15 years using GPS tracker collars. Where they turn up might just surprise you. Gehrt joins us to discuss Chicago's thriving urban coyotes.

Best-known for the movies Ray and An Officer and a Gentleman, director Taylor Hackford is in Chicago directing a musical stage show about the legendary Vegas husband and wife team, Louis Prima and Keely Smith. We get a preview.

We share what you had to say about construction on The 606 nearing completion and our panel of local rabbis discussing the Israeli election in tonight's viewer feedback.