Harnessing the power of the human body to prevent illness – that’s the goal behind a $100 million gift to the University of Chicago Medicine.

Here’s something that might surprise you: The best place in the entire state of Illinois to see birds during their spring migration is in the city of Chicago. 

Fifty years after Loving v. Virginia, depicted last year in the film “Loving,” a new study examines interracial marriages.

The clean economy: What is it, and how is Chicago faring? A new report tells the story.

Why some community groups are mounting opposition to the Obama Library's Jackson Park location and where they say it should go instead.

Watch the May 23, 2017 full episode of "Chicago Tonight."

After a nearly unanimous no-confidence vote in Chicago Public Schools CEO Forrest Claypool, members of the Chicago Teachers Union took to City Hall Tuesday to push Mayor Rahm Emanuel to fire the school district chief.

Democrats in the Illinois Senate on Tuesday passed what could be the state’s first complete budget in two years and a revenue package that includes a 32-percent increase in the personal income tax rate. 

“Chicago's Very Own," WGN-TV could be soon owned by a politically active, conservative broadcast company based in Baltimore.  

As many Chicago cyclists are starting to shake off the winter cobwebs and get back on their bikes, we take a look at what they can expect this summer. 

The BiAffect app, the winner in a contest using Apple’s Research Kit, was developed to predict manic episodes and depressive moods in people with bipolar disorder, based on how they interact with their cellphones.

It’s not often that an Oscar winner for best picture gets translated to the stage. “Shakespeare in Love” is getting its U.S. premiere at Chicago Shakespeare Theater. 

Though best known for his multimedia contemporary art, Chinese dissident Ai Weiwei is also a prolific photographer. We visit an exhibition at the Museum of Contemporary Photography showcasing his work.