John Prine talks about his storybook journey to become one of the country’s most revered songwriters, and why he’s come home to his alma mater, Proviso East High School, for a special two-night concert.

Northwestern professor, author and performance artist E.

We hear from two people who know Supreme Court nominee Elena Kagan, including Judge Abner Mikva, for whom she was a law clerk.

A federal judge has ruled that two genes, which are linked to breast and ovarian cancer, cannot be patented and has struck down the previ

We introduce you to an important -- and often overlooked -- American artist who painted scenes of nightlife on Chicago's South Side in th

Controversial Chicago Pastor Carlton Pearson discusses his new book, God is not a Christian, nor a Jew, Muslim, Hindu...

We meet a Chicago man who wants to change the way America thinks about table tennis.

President Barack Obama has nominated Solicitor General Elena Kagan for the U.S. Supreme Court.

Carol Marin sits down with the Republican candidate for governor, Bill Brady.

Will new work rules at McCormick Place keep conventions in Chicago?

Nearly every Friday for three and half years, two Chicago nuns have led a vigil at the place where undocumented immigrants are processed

He's fighting obesity with his so-called "50 Million Pound Challenge." We talk to bestselli

Joel and his panel discuss the week's top headlines: Lawmakers are still wrangling over the state budget in Springfield; we'll take a clo

Carol Marin sits down with world-renowned primatologist Dr. Jane Goodall.

We find out what state legislators were working on today in Springfield.