Chicago teachers formally give a 10-day strike notice to the Chicago Board of Education. Why the mayor and schools chief think they can avoid a walkout.

A baby has been born with the DNA of three parents. We hear about the promise the technique offers for avoiding some birth defects, and the ethical concerns it raises.  

Chef Rick Bayless joins us with recipes for pork tacos and a tequila-based cocktail of his own invention.

This year's heated election is spilling over into the workplace. Are there any benefits to talking about politics at work? 

Some parents are skipping family events and stockpiling paid time off to make sure they're able to watch children during a possible teacher's strike next month.

The 1960s Chicago filmmaker known as the Godfather of Gore died earlier this week. We look back on the work of this cult figure.

From a glowing photo exhibition to vegan chefs and cat videos on the big screen, this weekend’s roundup includes fun fall events both indoors and out.

The Lincoln Park Zoo gave journalists a sneak peek of the new African penguin exhibit, which aims to replicate the birds' natural habitat in southern Africa.

The CTU plans to serve CPS its 10-day strike notice Thursday for a possible Oct. 11 walkout. We hear more about the plan from CTU Vice President Jesse Sharkey.

He may not have had flattering words for Chicago during Monday's presidential debate, but Donald Trump on Wednesday hit Chicago and the suburbs for rallies and fundraisers.

A federal judge blocks Election Day voter registration in Illinois, but Attorney General Lisa Madigan says she will appeal the ruling. We hear arguments on both sides of the case.

Watch the Sept. 28, 2016 full episode of "Chicago Tonight."

A proposal designed to eliminate overcrowding at Mount Greenwood Elementary by shuffling around neighboring schools has been met with disdain by local parents.

Four parents sued Cook County because their sons were held in juvenile detention for days without a hearing. Now that common practice is changing. Assessing the impact of that move.

Crain’s Chicago Business managing editor Ann Dwyer reports on the McDonald's of the future, Rick Bayless's new business recipe and why online retailing giant Amazon is partnering with Merz Apothecary.