Scientists say there are more bacteria in the ocean than stars in the universe, yet little is known about them. A new study outlines the “crazy idea” that led to a project described by one scientist as the “Google database for microbes.”

Lady arm wrestlers, a massive art fair, sudsy brews and sea lions usher in the weekend. Here are 10 things to do in and around Chicago.

Watch the Oct. 31, 2017 full episode of "Chicago Tonight."

We take a closer look at the race for governor in both parties, and the surprise candidate running for attorney general.

Lobbyist Denise Rotheimer, who is also running as a Republican for state representative, testified that she was the victim of “mind games” and untoward comments made by state Sen. Ira Silverstein, D-Chicago.

An investigation uncovers a disturbing gap in how much local communities charge their residents for water. We discuss the findings with Chicago Tribune reporters Cecilia Reyes and Ted Gregory.

Former President Barack Obama and first lady Michelle Obama are back home in Chicago to launch the inaugural Obama Foundation Summit. 

Up to this point, it wasn’t certain that a challenger would emerge from the intraparty revolution Gov. Bruce Rauner ignited when he signed an abortion law in late September. There’s no ambiguity now.

Walgreens and CVS try to fend off competition from Amazon. Reporter Bruce Japsen joins us for a look at possible shifts in the pharmacy business.

Supporters of a bill vetoed this summer by Gov. Bruce Rauner are calling on legislators to override that action next month in the hopes of expanding the use of gas tax funds to public transportation services and other improvements.

Former Northwestern professor Wyndham Lathem and his accomplice Andrew Warren, charged in the stabbing death of a Chicago hairstylist, will have their hearings scheduled together as their cases proceed.

Words of culinary wisdom from master pastry chef Jacquy Pfeiffer, co-founder of The French Pastry School.

Is Gov. Bruce Rauner about to get new competition in the Republican primary? 

Watch the Oct. 30, 2017 full episode of "Chicago Tonight."

The Chicago Tribune published a report Monday on the “rediscovery” of a long-forgotten 35 mm film in the National Archives. The story behind the incredible aerial footage of Chicago shot in August 1914.