After more than 25 years on Michigan Avenue, the cultural organization has moved into a spectacular new space on East Wacker Drive, expanding its mission and its footprint on the city.

A document promised to result in “real and lasting reform” for Chicago police is in the hands of a federal judge. The latest on the consent decree.

In the last two decades, only four drugs have been approved to treat Alzheimer’s symptoms, according to a new report. “I’m very optimistic that within 10 years we’ll have a breakthrough,” said Dr. Doug Williamson of biopharmaceutical company Lundebeck.

Twelve jurors have been selected. Eleven have been sworn in. Suspended Chicago police Officer Jason Van Dyke and his attorneys have one more day to decide if they want a jury trial or a bench trial, with opening arguments expected as soon as Monday.

The number of rescued cats at Chicago’s Animal Care and Control shelter reached a high of 300 earlier this week, prompting the agency to sound the alarm on social media.

There may soon be tidal waves in the race for Chicago mayor, should Cook County Board President Toni Preckwinkle run, or should County Commissioner Jesus “Chuy” Garcia take a second shot at the city’s top job.

Punk rock bands, tons of tacos, cultural celebrations, butterflies and yoga usher in the weekend. Here are 10 things to do in and around Chicago.

Watch the Sept. 12, 2018 full episode of “Chicago Tonight.”

Tap, rap, and a whole lot more when Collaboraction’s performance festival visits the West Side.

Campaigns are buying TV ads, web banners, and producing a wealth of videos for social media, and they’re using technology to target voting blocs with ever-increasing precision.

Longtime Apple watcher and former Chicago Sun-Times columnist Andy Ihnatko weighs in on the tech giant’s newest offerings.

Meet the South Side native whose line dance became a worldwide phenomenon.

The lead attorney for Chicago police Officer Jason Van Dyke says it’s too early to decide whether he will opt for a jury or bench trial. Meanwhile, day two of jury selection brought the total number to 10.

A viewer spots a Blue Island building with an image of three chain links on its facade. Geoffrey Baer has the scoop on the odd fellows behind that insignia in this encore edition of Ask Geoffrey.