A shooter with a rifle opened fire from a nearby roof onto a U.S. Immigration and Customs Enforcement location in Dallas on Wednesday, killing one detainee and wounding two others in a transport van before taking his own life, authorities said.

Organizers and local leaders push to reopen Weiss Hospital in Uptown. And a new campaign to address Chicago’s opioid epidemic.

Lawmakers said the owner of Weiss Memorial Hospital filed to appeal Medicaid funding cuts that led to the hospital’s closure last month.

Vending machines containing free Narcan will be placed at five CTA stations throughout Chicago as part of a six-month pilot initiative between the CTA and Cook County Health.

A federal judge has rejected the Trump administration’s attempts to force states to comply with unlawful immigration conditions in order to obtain federal disaster relief funding, ruling such efforts are "unconstitutional” after officials from Illinois and other states sued.

The unanimous vote by the City Council’s Housing and Real Estate Committee means a yearslong fight to prevent longtime residents from being pushed out of South Shore is one step away from victory.

Sister Jean provided a message to Loyola students and faculty on her 106th birthday on Aug. 21, where she said she had a “bad summer cold and other health issues” that made her unable to celebrate her birthday on campus this year.

A suburban fire chief has asked federal authorities to remove fencing placed up around an Immigration and Customs Enforcement processing center this week in Broadview.

Public school enrollment is projected to tumble 5.5% between 2022 and 2031, largely due to changing demographics, according to the National Center for Education Statistics. Other factors include the shift by some students to private education or homeschooling and some immigrant families’ decisions to leave the country.

Antimicrobial resistance occurs when germs such as bacteria and fungi gain the power to fight off the drugs designed to kill them. The misuse of antibiotics was a big reason for the rise — unfinished or unnecessary prescriptions that didn’t kill the germs made them stronger.

Dr. Richard Frye told The Associated Press that he’d been talking with federal regulators about developing his own customized version of the drug for children with autism, assuming more research would be required.

The recommendation bucks new and murky guidelines from the Centers for Disease Control and Prevention that recommend vaccines only for people ages 65 and older.

A Chicago police officer is accused of using his official credentials to purchase an assault weapon and another firearm in an attempt to smuggle them into Mexico.

Each Wednesday, WTTW News producer Josh Terry presents must-see live music shows from indie rock to jazz, country, hip-hop and more.

Grassroots organizing in response to “Operation Midway Blitz.” And a local event raises awareness for suicide prevention.