Preventing the rejection of organ transplants. Could new research hold the key to long-term success? Ash-har Quraishi takes a look in this edition of Scientific Chicago.

An airship crash, a murder mystery, and a bloody race riot. We look at 12 days of disaster in Chicago's history.

Master sommelier and Check Please! host Alpana Singh joins us to answer your wine and spirits questions.

High-profile attorney Dan Webb-- now special prosecutor in the controversial case involving Mayor Daley's nephew.

The city's inspector general is sounding the alarm on the mayor's proposed infrastructure trust ordinance. We talk to him about how he thinks it can be improved.

A group of aldermen and the Better Government Association want to rewrite the mayor's infrastructure trust ordinance. Carol Marin and her panel have more.

Governor Pat Quinn tackles the state's $80 billion underfunded pension system.  We'll get reaction to his plan from a union coalition and the Civic Committee of The Commercial Club of Chicago.

Former Soviet President Mikhail Gorbachev talks world peace with local high school students. Elizabeth Brackett has more on his visit and the World Summit of Nobel Peace Laureates.

A northwest side movie theater is among a handful of neighborhood cinemas on a new endangered buildings list--at the same time some other theaters are coming back to life.

We aske

Joel Weisman and his panel of journalists discuss the week's top headlines.

Need some ideas for what to do this weekend? Chicago Tonight knows what’s going on!

Gov. Pat Quinn lays out $2.7 billion in Medicaid cuts after a committee he appointed falls short of a plan.

The mayor delayed his infrastructure trust vote. Is he working behind the scenes trying to convince opponents to vote yes? Paris Schutz has the story.

The eagles have landed. We show you some of the first images of a pair of American Bald Eagles, and their newly hatched eaglets, nesting in a Cook County Forest Preserve.