James "Big Cat" Williams gives us his updated Super Bowl picks, now that the Seattle Seahawks have been eliminated.

Problems escalate for Boeing as Japan grounds its entire 787 Dreamliner fleet.

Less than a year after leaving office, former Gov. George Ryan is arrested and charged with corruption.

How does the CTA keep its trains and buses operating on time? How prepared is it for a major incident like a terrorist attack? We get a rare look inside the transit system's high-tech nerve center.

Lands' End founder Gary Comer dedicated much of his life to revitalizing his childhood home: Pocket Town, in Greater Grand Crossing. How much good has his $86 million (and counting) done? Chicago magazine editor Elly Fishman joins us with the story.

We learn winter gardening tips, and why now is the best time to look for signs of the Emerald Ash Borer, from Chicago Botanic Garden's Eliza Fournier.

The historic election of Barack Obama as the 44th President of the United States.

Gov. Rod Blagojevich is arrested at his home and charged with trying to sell Barack Obama’s Senate seat, among other crimes.

The Chicago City Council considers having taxpayers foot a $33 million bill to settle police misconduct cases. Paris Schutz has the latest news from City Hall.

Stolen computers, pornography and lunch program fraud. There's a new report outlining misconduct in city schools. We have the results.

Could the secret to good health and combating disease rest in the gut? In tonight's Scientific Chicago, Ash-har Quraishi tells us about an unusual procedure that could provide some answers.

Chicago Tonight spoke with Dr. Stacy Kahn, who specializes in the treatment of digestive diseases at the University of Chicago Medicine Comer Children's Hospital, about Fecal Microbiota Tranplants.

The unbelievable landing of the Curiosity Rover on Mars capped a year of fascinating space exploration.

A new book explores the racial identity of Mexicans and Puerto Ricans in Chicago after World War II -- neither white nor black, but sometimes a buffer between the two.

We take a new look at the original funny ladies in TV history.