Congresswoman Tammy Duckworth announced she will run for Senate in 2016 against incumbent Sen. Mark Kirk. 

Indiana's passage of a so-called religious freedom law has sparked an angry backlash from those who assert that it gives license to businesses to discriminate against same-sex couples on religious grounds. Already there has been a massive backlash against the law, with leaders of business—including Apple's CEO Tim Cook—decrying the law.

First-term Ald. John Arena, a member of the City Council's Progressive Caucus and a frequent thorn in Mayor Rahm Emanuel's side, faces a runoff rematch with Chicago Police Lt. John Garrido in the race to represent the northwest side's 45th Ward.

Tracking the history and treatment of cancer from ancient Egypt through today: we talk with Dr. Siddhartha Mukherjee, author of the book The Emperor of All Maladies: A Biography of Cancer, about a new three-part documentary produced by Ken Burns that begins airing Monday, March 30 on WTTW11.

Chicago's own Ethel Payne was the third African-American to ever receive White House press credentials–and she was only the second black woman to do so. We talk with the author of a biography about the importance of her legacy.

The School Project is a Chicago-based documentary series that is tracking the past and present status of the city's public school system. The fourth episode  focuses on the battle over standardized testing.

We share what you had to say about Jesse Jackson Jr.'s release from prison, contract negotiations between CPS and CTU, and Chicago's urban coyotes in tonight's viewer feedback.

On this edition of Chicago Tonight: The Week in Review with Joel Weisman, two Aurora men are arrested for allegedly plotting to attack an Illinois military base, mayoral candidates face off in a televised debate, and the CTU issues a list of demands.

Joel Weisman and his panel of journalists continue their conversation online with a discussion of journalists appearing in political advertising.  

Watch a mariachi opera set in 1910 Mexico; enjoy a musical set in 1950s Las Vegas; and kick off the running season in present day Grant Park. Chicago Tonight ​has your weekend picks.

Two local men were arrested on charges of aiding the ISIS terror group.

Former Illinois Rep. Jesse Jackson Jr. has been released from a federal prison in Alabama after his 2013 conviction for tax evasion and misuse of campaign funds. His next stop will be a halfway house, likely located in the Washington, D.C. area.

Contract negotiations between the Chicago Teachers Union and Chicago Public Schools have formally begun – and the union’s initial list of demands is not the traditional one. We have the details.