The Cancer Moonshot initiative being led by Vice President Joe Biden aims to accelerate the pace of cancer research and the development of new treatments. We talk to the University of Chicago professor who is a key player in that effort.

Technology is creating challenges for today's parents. A local author has advice for how parents can plug into the changing world of social media, apps and the online world.

Some restaurants are moving away from traditional tipping. The practice can be more stable for servers but could also mean less income. We discuss trends in tipping with a Loyola University economist.

A group gathered Wednesday to mark the 198th anniversary of the death of Jean Baptiste Point DuSable, Chicago’s first non-native settler, and push for the completion of a long-delayed park in his name.

Salute the season with an authentic Oktoberfest celebration, get crafty in Wicker Park, gear up for the Bears, stay up late for an all-night concert of classical Indian music and more this weekend.

The rank-and-file members of the Chicago Teachers Union have already approved a strike, but the union is planning a second vote. Find out why.

Architecture critic Blair Kamin on the future redevelopment of the Tribune Tower and the rise of a new Jeanne Gang-designed addition to the Chicago skyline.

Aldermen are set to vote to raise water taxes by 30 percent to fix city pensions. But new analysis shows it won't be nearly enough, and that has some council members saying they were duped by the mayor.

Watch the Sept. 7, 2016 full episode of "Chicago Tonight."

Hear from state lawmakers about where remap reform goes after a recent proposal was shot down by a divided Illinois Supreme Court. 

Are some wealthy residents of Cook County taking advantage of laws meant for the most vulnerable? We discuss the issue with a Chicago Sun-Times watchdog.

Students at Chicago Public Schools have steadily improved their attendance and on-track-to-graduate rates while trimming back their annual dropout rate over the past five years, according to a new district progress report.

As homicide rates in Chicago soar, a new street festival looks to highlight the positive side of a South Side community that often makes headlines for crime.

Breast cancer patients and survivors often report forgetfulness and difficulty focusing after chemotherapy. A recent study analyzes these symptoms, commonly referred to as “chemo brain.”