Sara Sayigh, a 60-year-old librarian on the historic DuSable High School campus, was one of nearly 250 educators and support staff CPS laid off this week because of shrinking budgets and declining enrollment.

He was a literary giant who chronicled the seedy side of the city. We talk with the author of a new biography about Chicago writer Nelson Algren.

The 11th annual festival is underway. Get a preview of this year's artists and hear a performance by guitarist Iliana Matos.

We hear from three business leaders on their efforts to help Chicago reduce violent crime.

The eastern massasauga rattlesnake, also known as the “swamp rattler,” produces venom more toxic than most other rattlesnakes.

The story behind a new stage adaptation of an infamous–and fatal–boxing match that was televised in the 1960s.

Elsa Harris has played in Chicago churches since she was 12 years old and has performed around the world. We visit this “legend of Chicago gospel.”

Watch the Oct. 3, 2016 full episode of "Chicago Tonight." 

Only 35 days until Election Day and newspapers across the country are making some surprising endorsements. We talk with local editorial board members. 

The Field Museum's Chief Curiosity Correspondent has a new show and she's here to tell us all about it.

Some Chicago Public Schools students may be missing their teachers as more than 250 layoff notices go out Monday.

The YMCA and other community organizations across the city plan to hold strike camps for CPS students if the district and Chicago teachers can't reach a contract agreement by next week.

The rare psychiatric disorder increases the risk that a mother will harm herself or her newborn, according to a recent study. A local psychiatrist explains the seriousness of the illness and how it differs from the more commonly studied postpartum depression.

The Shedd Aquarium is calling on President Barack Obama to sign legislation that aims to curb the highly lucrative, international business of illegally trading endangered and threatened animals.