The University of Illinois at Chicago, Northwestern Memorial Hospital and the University of Chicago Medicine will join forces to conduct clinical trials designed to improve outcomes for patients with life-threatening emergencies as part of a newly formed national network. 

We preview the start of the Cubs’ playoff run with sports reporter Cheryl Raye Stout.

Food trucks, vintage VHS, marathon runners and South Side films usher in the weekend. Here are 10 things to do in Chicago.

The American Civil Liberties Union and other groups are suing the city and the Police Department so they can be part of reform talks. The suit alleges that brutality “is magnified for people with disabilities.”

Watch the Oct. 4, 2017 full episode of "Chicago Tonight."

Geoffrey Baer explores an eccentric architect’s wacky proposal for the World’s Fair in this encore edition of Ask Geoffrey.

The Nobel Prize committee called it “a discovery that shook the world.” A local scientist explains gravitational waves.

“Blockbuster” and “epic” are the words being used to describe the cases on the U.S. Supreme Court docket this term. We discuss the key cases.

In one of Cook County Jail’s maximum security units, some detainees are given access to pens for the towering task of writing their memoirs. How these men are earning a new label: authors.

A new book by a Chicago community activist and mentor explains how cities can become safer and more equitable, and why we all have a stake in our neighborhoods. 

It looks like an art project, but a seven-floor structure at Lincoln Park Zoo is outfitted with logs, bricks, sticks and other materials to provide cozy spaces for insects to nest.

Is there a connection between losing the ability to smell and a greater risk of dementia? A co-author of a new University of Chicago study says it “may be an important early sign.” 

A new charge against 28-year-old suspect Brendt Christensen opens up the possibility of the death penalty for the Champaign man charged in the disappearance and murder of a Chinese student.

Tommy Shimoda, 24, won gold and bronze medals in speed skating at the Special Olympics World Winter Games this year in Austria. This week, he was inducted into the Chicagoland Sports Hall of Fame, becoming the first Special Olympics athlete to receive the honor. 

The inspector general calls it a “culture of abuse.” How he says police officers are gaming the system to collect millions in overtime pay.