With the race for a vaccine underway and President Donald Trump claiming one could be available before the November election, Gov. J.B. Pritzker reiterated Wednesday that safety would guide the state’s reopening.

The City Council on Wednesday approved a $4.5 million package designed to prevent the planned Obama Presidential Center in Jackson Park from supercharging gentrification in Woodlawn.

A Cook County judge has denied bond for the 18-year-old high school student who is accused of calmly and methodically stabbing a Walgreens employee to death Sunday inside the Wicker Park store where she worked.

With people spending more time outdoors to prevent the spread of COVID-19, the state’s top doctor is urging people to protect themselves from the mosquito-borne West Nile virus.

The Chicago City Council voted 46-4 Wednesday to ban the sale of most flavored liquid nicotine products in Chicago, after an effort to prohibit the sale of all flavored tobacco products failed to advance.

Watch the Sept. 9, 2020 full episode of “Chicago Tonight.”

The top U.S. infectious disease expert said AstraZeneca’s suspension of final testing of its COVID-19 vaccine candidate shows “one of the safety valves” built into the studies to spot any potential problems.

The Chicago Historic Resource Survey, completed in 1995, has been an invaluable tool for preservationists. But it’s beginning to show its age, and the lack of sites of significance to the Black and Latino communities is notable.

The coronavirus has shuttered concert venues around the world, but that hasn’t stopped artists and musicians from finding new ways to share their work. Soprano Renee Fleming tells us about Lyric’s upcoming concert.

What you need to know about the race for a coronavirus vaccine.

The Chicago Commission on Landmarks unanimously approved preliminary landmark status for Emmett Till’s former home, calling the red brick two-flat a “modest home that is monumentally important.”

Big technology stocks tumbled again on Tuesday, continuing the Icarus-like flight path for companies that just a week ago were the high-flyers carrying Wall Street to record heights. 

R. Kelly can remain behind bars awaiting multiple trials on child pornography and other charges in three states, an appeals court in New York said Tuesday.

Chicago police have charged Sincere Williams, 18, with first-degree murder in the fatal stabbing of a Walgreens employee as she was stocking shelves inside a Northwest Side store Sunday.

More than 1,650 organizations throughout the state have received grants through the fund, which distributed $7.5 million in its final round of funding to organizations primarily serving Black and Latino communities.