Inside the human body lives a community of microorganisms, bacteria, viruses and fungi known as the microbiome. Local professors talk about the importance of understanding the microbiome and the potential implications it could have on health and disease.

A new exhibit at the Museum of Science and Industry invites visitors to sail though time and explore the evolution of ship design. 

Watch the Nov. 15, 2016 full episode of "Chicago Tonight."

The Supreme Court under President-elect Donald Trump: Who will he nominate? And could the court actually keep him from doing some of things he wants to do?

Republican and Democratic state leaders are not seeing eye to eye after a meeting in Springfield. Amanda Vinicky joins us with the latest from the state capitol.

On the campaign trail, Donald Trump spoke often about immediately repealing the Affordable Care Act. Now, as president-elect, he appears to be changing his plan. A look at what might be ahead for Obamacare. 

Learn about a major Shakespeare exhibit at the Newberry Library and get an exclusive look at some rare artifacts that didn’t make the cut.

The moving and powerful life of Maya Angelou: A new film explores the many facets of the acclaimed poet and writer.

The former Chicago alderman was indicted Tuesday on charges of income tax evasion and impeding the IRS. He is expected to be arraigned before Thanksgiving.

A tough job, but hundreds of Chicago educators do it–a new report on making sure the best principals are on the jobs in Chicago Public Schools.

In the wake of Donald Trump’s election, mental health officials say a growing “public health crisis” has emerged. Meanwhile, Mayor Rahm Emanuel assures immigrants that Chicago will remain a sanctuary city.

Chicago Tonight visits a little shop in Chicago for a look at how to rejuvenate pitched percussion instruments – and to get a history lesson in concert tuning.

Watch the Nov. 14, 2016 full episode of "Chicago Tonight."

The whole world is watching. Just how does America transition from one presidential administration to another? We get an inside look.

Did America have a woman president nearly a century ago? The author of a new book argues that President Woodrow Wilson’s wife Edith was more than a first lady.