Abuse of opioid-based prescription pain killers, heroin and synthetic substitutes are killing more Americans than ever before. 

Watch the Dec. 15, 2016 full episode of "Chicago Tonight."

Chicago’s air traffic controllers and the pilots they guide have a new way of communicating that officials say will improve speed and safety. We explain how it works.

Presidential libraries from FDR and Hoover to Reagan, Clinton and Bush. How they tell a president’s story, and the relationship they create with visitors.

It’s the most wonderful time of the year for word nerds! We take a look at the candidates for 2016’s word of the year.

Fewer people are smoking in Illinois than other states but more are drinking excessively, according to a report released Thursday that ranks Illinois as the 26th healthiest in the nation. 

More than 170 schools in the greater Chicago area were closed or delayed their starting times Thursday due to subzero temperatures and bitter wind chills. But even as temperatures plunge below zero this week, Chicago Public School students probably shouldn’t count on any extra time off leading up to their holiday break.

Viewers were nearly unanimous in their disapproval for the six state lawmakers suing Illinois for their paychecks. 

Taiko drummers, holiday cheer, bird watchers and Beethoven usher in the weekend. Here are 10 things to do in Chicago.

Watch the Dec. 14, 2016 full episode of "Chicago Tonight."

For 83 years, the famous and not-so famous fell in love with the Cape Cod Room. But the iconic Chicago restaurant will soon serve its last meals. We tell you why.

A new DePaul University study suggests that it may be safer for bicyclists to roll through stop signs and red lights rather than coming to a full stop. The practice, legal in Idaho, is known as an “Idaho stop.”

Days away from the 40th anniversary of his death, UIC announced it will offer a new honors course next semester on Chicago and its late mayor’s role in local, national and international politics in the late 1960s.

Meet a medical doctor who moonlights as a magician. Northwestern University’s Dr. Ricardo Rosenkranz joins us to explore the mysteries of medicine and magic.

With temperatures plunging into single digits this week, the city is reminding residents that they can seek refuge in designated warming centers.