The U.S. top trade negotiator will begin talks with the World Trade Organization on ways to overcome intellectual property issues that are keeping critically needed COVID-19 vaccines from being more widely distributed worldwide, two White House officials said Sunday.

With Janice Jackson stepping down as CEO of Chicago Public Schools, Mayor Lori Lightfoot will now be on the hunt for the 10th person to head the district since the position was created in 1995. Here’s a look back at the people who’ve held the spot and where they are now.

Thousands of COVID-19 vaccines wasted at Walgreens and CVS. Crain’s Chicago Business editor Ann Dwyer takes us behind the headline of that story and more.

Timothy Nielsen, who is accused of trying to run over a group of friends celebrating a birthday in Logan Square on Saturday, allegedly told a witness, “Watch what I’m going to do,” before he sped his truck toward the victims.

Cook County officials are marking Small Business Week, which runs through Saturday, with the launch of a new initiative aimed at supporting small businesses as they recover from the COVID-19 pandemic.

In the first Biden administration rule aimed at combating climate change, the Environmental Protection Agency is proposing to phase down production and use of hydrofluorocarbons, highly potent greenhouse gases commonly used in refrigerators and air conditioners.

One-on-one with CPS CEO Janice Jackson as she announces her resignation. Communities push for greater political representation. A push to rename Lake Shore Drive. And an encounter with a giant insect.

The next round of grants, set to open this month, could provide residents with 15 months of rental assistance to cover past-due rent from the previous 12 months and three additional months.

Travel to the European Union is currently extremely limited except for a handful of countries with low infection rates. But with the summer tourist season looming, the European Commission hopes the new recommendations will dramatically expand that list.

This month’s Black Voices Book Club selection traces the civil rights trail blazed by Dr. C.T. Vivian. We discuss Vivian’s legacy with Steve Fiffer, the co-author of “It’s in the Action: Memories of a Nonviolent Warrior.”

The power of public art for a community. Our latest Black Voices book club selection about a civil rights activist. Harmonica lessons with legendary blues musician Billy Branch.

Themes of justice, pride and community have blossomed in murals along Chicago’s streets and storefronts, creating a constantly evolving and thought-provoking backdrop to a tumultuous year.

Tribal leaders in northeastern Wisconsin were in shock Sunday hours after a gunman opened fire at a their casino complex, killing two people and wounding another in what witnesses described as a hailstorm of bullets.

Make telemedicine your first choice for most doctor visits. That’s the message some U.S. employers and insurers are sending with a new wave of care options.

Chicago has seen a significant increase in shootings and homicides so far this year, compared with the first four months of 2020, police said Saturday.