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We preview the start of the Cubs’ playoff run with sports reporter Cheryl Raye Stout.

(Credit: Northwestern Medicine)

The University of Illinois at Chicago, Northwestern Memorial Hospital and the University of Chicago Medicine will join forces to conduct clinical trials designed to improve outcomes for patients with life-threatening emergencies as part of a newly formed national network. 

(EMR / Flickr)

Stephen Paddock, the gunman who opened fire on thousands of concertgoers in Las Vegas late Sunday night, had booked two rooms in Chicago overlooking Grant Park in August, during Lollapalooza, according to a report from TMZ.

The Cook County board president used her annual budget address Thursday to warn commissioners and the public that repealing a tax on sugary drinks will take the county down a path of “fiscal uncertainty” that will result in layoffs and cutting “essential services.”

“Brown Girls” director Sam Bailey, left, and co-creator Fatimah Asghar (Credit: Alexus McLane)

A web series that debuted in February has already been picked up by HBO. Made in Chicago, it highlights the friendships between young women of color. We talk with the award-winning poet who co-created the series, and an actor from the show.

Watch the Oct. 5, 2017 full episode of "Chicago Tonight."

Mayor Rahm Emanuel says the Chicago Police Department’s murder clearance rate is “unacceptable,” as are details out this week describing an “abuse of culture” surrounding police overtime pay. Watch the interview.